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\n\tCleto Escobedo III, childhood friend of Jimmy Kimmel<\/a> and longtime bandleader of Jimmy Kimmel Live<\/a><\/em>, has died at age 59. Kimmel announced the news on his Instagram Tuesday afternoon. The cause of death was not disclosed.<\/p>\n \n\t\u201cEarly this morning, we lost a great friend, father, son, musician and man,\u201d Kimmel wrote alongside sharing a photograph of Escobedo with his saxophone. \u201cTo say that we are heartbroken is an understatement. Cleto and I have been inseparable since I was nine years old. The fact that we got to work together every day is a dream neither of us could ever have imagined would come true. Cherish your friends and please keep Cleto\u2019s wife, children and parents in your prayers.\u201d<\/p>\n \n\tThe news comes shortly after Entertainment Weekly<\/a> <\/em>confirmed that the Nov. 6 episode, which was replaced with a rerun on little notice, was postponed due to a \u201cpersonal matter\u201d related to the host.<\/p>\n \n\tEscobedo has led the Jimmy Kimmel Live! <\/em>house band, named Cleto and the Cletones, since the show premiered in 2003. Escobedo played the alto, tenor, and soprano saxophones and occasionally sang. The pair first met growing up in Las Vegas. They were neighbors.<\/p>\n \n\t\u201cCleto had a bicycle with a sidecar attached to it,\u201d Kimmel said in a 2016 segmen<\/a>t dedicated to his friend\u2019s 50th birthday. \u201cWe called it the side hack. I would get in the sidecar and then Cleto would drive me directly into garbage cans and bushes.\u201d<\/p>\n